From a Saliva Sample to Molecular Insights About Your Periodontal Health
UniquePerioSignature™ uses laboratory-based qPCR technology to detect and quantify targeted periodontal-associated bacteria, providing molecular information that you and your dental professional can consider alongside clinical findings. Order Your Kit
Four simple steps
Order Your Kit
Order online or get one from your dentist. Every kit includes SalivaPreserv™, our DNA-stabilizing collection tube.
Collect Your Sample
Collect your saliva sample at home using the SalivaPreserv™ tube—no swabs or dental visit required. Sample collection typically takes about 2 minutes.
We Run the Analysis
Your sample goes to our CLIA-certified lab, where qPCR technology detects and quantifies 5 key periodontal pathogens.
Get Your Results
Within approximately two business days after the laboratory receives your sample, you will receive a report showing the levels of the targeted periodontal-associated bacteria. Share your results with your dental provider for interpretation alongside your clinical findings and to discuss appropriate next steps. Also check this - Understanding Your Results.
Not a guess. A count.
Traditional periodontal assessments, including probing and visual examination, provide important clinical information. Molecular testing can complement these assessments by identifying and quantifying targeted periodontal-associated bacteria.
UniquePerioSignature™ uses qPCR (quantitative polymerase chain reaction) technology to detect and quantify targeted periodontal-associated bacteria in saliva, providing quantitative results for each bacterial target included in the panel.
What We Test For
Test Kit Ordering & Sample Collection
Order Your Kit
Request your UniquePerioSignature test online, and it will be shipped directly to your home.
Collect your sample
Provide a small saliva sample into your SalivaPreserv™ tube. Your DNA stays stable at room temperature for up to 14 days, so there is no rush to ship it back to our facility.
Sample check-in & processing
Your kit is received and processed at our CLIA-certified facility, where our clinical team securely logs it in and prepares the sample for advanced qPCR analysis.
Results reported
Your personalized Test Result Summary is generated. This report clearly displays your specific bacterial counts and benchmarks them against healthy, moderate, and high-positive reference ranges.
Review your report with your health care professional.
Share the report with your healthcare provider provider. Your healthcare provider will use these precise molecular results, alongside their own physical clinical exam to recommend a highly personalized and effective care plan. Also check this - Understanding Your Results.
Your results, explained simply
Your report groups your bacterial levels into a color-coded risk zone, so you know exactly where you stand - and what to do next.
Green Zone - Low Risk
Your mouth is in a healthy, balanced state. Keep up your routine and daily maintenance.
Yellow Zone - Moderate Risk
Some pathogens are elevated. Your dentist may recommend a cleaning and closer monitoring.
Red Zone - High Risk
Elevated bacterial levels may be considered alongside clinical findings to support periodontal risk assessment and inform appropriate clinical considerations.
Quick answers
Do I need to go to a dental office to take this test?
No. You collect your saliva sample at home in under 5 minutes. Some clinics also offer in-office collection.
How accurate is qPCR compared to traditional exams?
qPCR directly measures bacterial DNA, giving a precise count rather than a visual estimate. It's used alongside - not instead of - your dentist's clinical exam.
How often should I retest?
Every 6 months at your regular dental visit, or sooner if symptoms appear or your dentist recommends it.
Is this test FDA approved?
This is a laboratory-developed test performed under CLIA# 45D2313828. FDA clearance isn't required for this type of clinical laboratory testing.
Ready to know what's really going on in your mouth?
Order your UniquePerioSignature™ Panel today and get lab-grade clarity in 2 days.
Order Your Kit - $99