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The Science
Detects and quantifies targeted periodontal pathogens that may be present before visible clinical signs, providing insights to support periodontal health assessment.
Identifies which targeted bacterial species are detected and their measured levels. No more guesswork or generic assumptions about your bad breath or gum health.
Each report translates your bacterial profile into a clear, easy-to-understand overview that you can share with your health care provider to support a more informed, personalized discussion about your oral health.
SCIENCE. QUALITY. PURPOSE.
AT HOME SALIVA TESTING
We don't overwhelm you with a complex map of your entire microbiome. Instead, we test for the key "bad actor" pathogens that act as a direct proxy for oral dysbiosis, giving you a clear look at whether your patient's oral ecosystem is out of balance.
Understand the exact bacterial risk factors unique to your mouth, not generic averages. Receive a crystal-clear breakdown of what is actually happening beneath your gumline so you can easily identify your baseline oral health metrics.
Act on real data, not guesswork. Spotting hidden bacterial shifts early gives you the clear insights you need to consult your dentist and protect your smile before minor issues become irreversible.
Track changes over time with clear, data-backed reports. Share your personalized pathogen profile with your dentist to support informed discussions about your oral health.
TEST. UNDERSTAND. PERSONALIZE.
HEALTHY GUMS. HEALTHIER YOU.
The bacteria in your mouth don't stay there. Research links oral pathogens to heart disease, diabetes, and Alzheimer's. Catching them early changes everything.
Identify hidden, harmful bacteria long before visible symptoms appear.
Your oral microbiome is connected to your overall health. Research has identified associations between periodontal pathogens and several systemic conditions.
Receive an easy-to-read, data-backed bacterial breakdown to share with your dentist.
Monitor your bacterial baseline over time to see how your oral ecosystem improves.
Science-Backed
Built on peer-reviewed research.
Laboratory-Validated Testing
Reliable. Accurate. Quality you can trust.
AI-Assisted Insights
Advanced technology. Human expertise.
Designed for Healthcare Professionals
Supporting better clinical assessment.
Molecular Insights. Informed Clinical Assessment.
WHAT'S TESTED
Every strain was selected for a specific function, not added to pad a label.
Detects and quantifies the 5 specific, aggressive bacterial strains (Aa, Pg, Td, Tf, and Pi) responsible for driving periodontal disease, active gum infections, and chronic bad breath. Unlike standard dental exams that rely on visual assessment alone, the UniquePerioSignature™ Panel identifies exactly which pathogens are present and at what levels, giving you and your clinician a precise, data-backed picture of what is actually happening in your mouth.
Catches microbial imbalance before bone loss appears on X-rays. By the time radiographic evidence of damage becomes visible, periodontal disease has often already progressed past the point of easy intervention. Salivary diagnostics detect bacterial activity at the source earlier, more accurately, and without the guesswork that comes with relying on symptoms alone.
Flags oral bacteria clinically linked to heart disease, diabetes, and chronic inflammation. The bacteria driving gum disease do not stay confined to the mouth. Research has established connections between periodontal pathogens and serious systemic conditions. Identifying these bacteria early gives you the opportunity to address oral dysbiosis before it contributes to broader health risks.
Every report translates your complex bacterial profile into a clear, easy-to-read overview. Take this personalized data directly to your dentist so they can design a precise, highly targeted treatment plan just for you.
Disclaimer: Statements regarding dietary supplements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.
AT-HOME ORAL MICROBIOME TESTING
Collect your saliva sample at home and send it to a CLIA-certified laboratory for qPCR analysis. The test provides quantitative results for five targeted periodontal microorganisms.
YOUR TESTING JOURNEY
From at-home collection to quantitative laboratory results.
Collect your saliva sample at home by following the instructions included with your kit.
Register and activate your kit using the links provided after you place your order.
Your saliva sample is analyzed in a CLIA-certified laboratory using qPCR to quantify five targeted periodontal microorganisms.
Receive a report showing quantitative results for the five targeted microorganisms. Discuss your results with a qualified dental professional alongside your clinical findings.
CLIA-Certified Lab | Collection Kit Included
Tax included where applicable.
Shipping Restrictions: Due to state medical and laboratory regulations, we are currently unable to ship the UniquePerioSignature Panel for Direct-to-Consumer testing to AL, CA, GA, HI, IL, MD, ME, NJ, NY, PA, RI, or SC. We apologize for any inconvenience
EVERYTHING YOU NEED TO KNOW
Click each section to learn more about what's included and how it works.
A convenient at-home saliva collection kit designed to provide quantitative microbial information on five targeted periodontal microorganisms using molecular testing. A kit contains Saliva sample collection
tube, biohazard bag with absorption pad and the barcode label.
Once you order the kit. You will receive the email message with instructions with your next step.
Your Next Steps:
1. Watch for Your Kit to Arrive
Your testing kit will be shipped directly to you. The pack contains the Saliva collection kit pack and the prepaid shipping envelope.
2. Register Your Kit using a registration link
3.Activate Your Kit using an activation link
4. Collect Your Saliva Sample
Follow the sample collection instructions carefully:
View Saliva Collection Instructions
5. Return Your Sample
Return your completed saliva sample using the provided return shipping instructions.
Important: This activation code is valid for one testing kit and can only be redeemed once. The important point is that at-home collection does not mean the testing itself is performed at home. The saliva sample is collected at home and then analyzed in the CLIA-certified laboratory using qPCR.
Receive a report showing quantitative results for the five targeted microorganisms. Results should be considered alongside clinical findings by a qualified dental professional for the follow-up treatment.
FAQs — Everything You Need to Know
Learn about SalivaPreserv™, home saliva testing, sample collection, usage, storage, safety, molecular diagnostics, and more.
Disclaimer: The UniquePerioSignature™ Panel is intended for use by qualified healthcare professionals. Test results should be interpreted together with clinical findings, patient history, and other diagnostic information. This laboratory-developed test (LDT) is performed in a CLIA-certified, high-complexity laboratory and has not been cleared or approved by the U.S. Food and Drug Administration.
Learn more → Medical & Laboratory Disclaimers
